I asked how many eggs I could expect as a 36-year-old with an AMH of 0.76. The answer was not always accurate; it said 4-8 eggs, but I ended up getting 10.
I told it my baseline AFC (Antral Follicle Count, which works in tandem with AMH), and it got closer to my results.
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ChatGPT / Screenshot by CNET
A blastocyst is the rapidly dividing ball of cells that represent embryo development. It's an important milestone in the IVF process, post-egg retrieval. The 40-60% making it to blastocyst was inaccurate, at least for my age group. My clinic told me it's closer to 30% (likely somewhere between 20-40%).
I asked ChatGPT to adjust the numbers accordingly. Then it said, of the 1-3 blastocyst embryos, 0-1 would be genetically normal. I ended up getting one, so it was right.
The interesting thing is that on my last ultrasound before the retrieval, I actually had 15 follicles, but I ended up with 10 eggs, 7 of which were mature/fertilized. Two made it to blastocyst: a day 5 BB grading and a day 7 BC grading. One was a euploid, which is a genetically tested embryo that came back normal - the ultimate IVF prize.
I asked ChatGPT what the embryo grading system meant.
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ChatGPT / Screenshot by CNET
Unfortunately, both my fresh transfer and frozen embryo transfers failed, so I asked ChatGPT for advice.
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ChatGPT / Screenshot by CNET
Wow, it said I'd need five to eight cycles to get three healthy embryos. It looks like I'm in it for the long haul at this age. ChatGPT mentioned Omnitrope, an injectable growth hormone, which is something I'm going to bring up with my clinic.
Asking AI silly questions about the process
What's also been helpful about having ChatGPT is asking "silly" questions that I wouldn't ask my physician. For example, does IVF use up all my eggs?
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ChatGPT / Screenshot by CNET
AI is good for busting myths like this, but always double-check with your clinical team because AI can hallucinate and make up answers.
Next, I asked ChatGPT what it would change for the second cycle, as well as what I should ask my team in order to have success in my next round:
Prompt: "I just turned 37. My AMH is 0.76 and AFC is 9. This is what they measured in my final ultrasound before the retrieval:
6.5 lining, 15 follicles (trigger night)
Right - 18, 18, 21, 22, 13, 10, 1 less than 10
Left - 17, 21, 11, 11, 13, 24, 22, 1 less than 10
I got 10 eggs, 7 mature/fertilized, 2 blasts (day 5 and day 7), but both are likely to be abnormal. What can I change for next time to get better success? What questions should I ask my clinic?"
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ChatGPT / Screenshot by CNET
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ChatGPT / Screenshot by CNET
There's a lot of helpful information here -- though again, don't start taking supplements or vitamins based on AI's advice. Always ask your doctor first before you start taking these. But AI's stats are good for expectation setting.
Using AI to help weigh up IVF finance decisions
Knowing that I'll need more cycles, I shifted the conversation to finances. It gave some options (though you'll need to verify the information given before making any important decisions).
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ChatGPT / Screenshot by CNET
It also confirmed my fears about importing US donor sperm into Australia, which is either not possible or extremely costly. I asked what the best low-cost clinics with good labs are in the US.
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ChatGPT / Screenshot by CNET
Again, and I can't say this enough, verify all of this information with each clinic.
CNY has been suggested to me before, so I asked ChatGPT to provide advice on advocating for myself as a patient and what I need to keep in mind when switching to a low-cost clinic.
It gave some sage advice:
Come prepared with a one-page "patient brief" with my past protocols and progress.
Put everything into a spreadsheet and be my own project manager.
Join the CNY Facebook support group.
Work with a fertility coach.
Triple-confirm every step myself.
I even asked ChatGPT to provide a template for my patient brief, and it generated one for me, creating spaces for me to fill out my personal details, any diagnoses, preferred approaches, ovarian reserve and cycle data, past IVF cycle results, goals, advocacy points and protocol requests.
Pretty handy stuff for a patient. And to re-emphasize the point: Don't give ChatGPT any of your medical records. Ask it to generate a standard IVF patient brief that you can copy and paste into Word or a Google doc, and fill out those personal sections yourself.
Can AI fill in your IVF knowledge gaps?
While I'm still on the IVF journey, it has been helpful to have a tool I can turn to for potential answers and advice. However, my clinical team, the IVF subreddit and my fellow IVFers remain my go-to sources for support.
AI is not a replacement for my clinical team, and I would not use it to inform major decisions, but it can fill in some knowledge gaps. Take its advice with a grain of salt, and never give it your personal info.
Sable says the human part is the most important part.
"You can't do IVF well without the human contact part. You're going through something that is so emotionally fraught and core to your existence."
No ChatGPT model can clap when an embryo is transferred successfully or offer a hug when a cycle fails.