全球13亿人患病，代谢相关脂肪性肝病患病率30年间增长143%

Declaration of interests

M Carvalho reports other financial or non-financial support from LAQV/REQUIMTE, University of Porto, Porto, Portugal and FCT/MCTES under the scope of the project UIDP/50006/2020 (DOI:10.54499/UIDP/50006/2020) outside the submitted work. S Congly reports grants or contracts paid to his institution from AstraZeneca, Merck, Ipsen, Bausch Health, Oncoustics, and Boehringer Ingelheim; grants or contracts from Gilead Sciences Canada; consulting fees from Boehringer Ingelheim and GSK; participation on a data safety monitoring board or advisory board with AstraZeneca, Gilead Sciences Canada, and Boehringer Ingelheim; leadership or fiduciary roles in board, society, committee or advocacy groups, paid or unpaid with Canadian Association for the Study of the Liver on the Board of Directors, Alberta Medical Association on the Representative Forum, and Alberta Gastroenterology Society as President; all outside the submitted work. I M Ilic reports support for the submitted work from the Ministry of Science, Technological Development and Innovation of the Republic of Serbia (grant 451-03-137/2025-03/200110). N E Ismail reports leadership or fiduciary roles in board, society, committee or advocacy groups, unpaid, with the Malaysian Academy of Pharmacy, Malaysia as Bursar and Council Member, Malaysian Pharmacists Society Education Chapter Committee as Committee Member, and Information Technology Service Management Forum (itSMF) Malaysia Chapter as Deputy President; all outside the submitted work. J J Jozwiak reports payment or honoraria for lectures, presentations, speakers' bureaus, manuscript writing or educational events from Novartis, Adamed, Amgen, Boehringer Ingelheim, Servier, and Novo Nordisk outside the submitted work. K Krishan reports non-financial support from the UGC Centre of Advanced Study, CAS II, awarded to the Department of Anthropology, and RUSA 2.O grant awarded to Panjab University, Chandigarh, India, outside the submitted work. M-C Li reports grants or contracts from the National Science and Technology Council, Taiwan (NSTC 113-2314-B-003-002) and the “Higher Education Sprout Project” of National Taiwan Normal University; leadership or fiduciary roles in board, society, committee or advocacy groups, paid or unpaid with the Journal of the American Heart Association as Technical Editor; all outside the submitted work. S Lorkowski reports grants or contracts from dsm-firmenich (formerly DSM Nutritional Products) paid to his institution; consulting fees from Danone, Novartis Pharma, and Swedish Orphan Biovitrum (SOBI); payment or honoraria for lectures, presentations, speakers' bureaus, manuscript writing, or educational events from AMARIN Germany, Amedes Holding, AMGEN, AstraZeneca, Berlin-Chemie, Boehringer Ingelheim Pharma, Daiichi Sankyo Deutschland, Danone, Hubert Burda Media Holding, Janssen-Cilag, Lilly Deutschland, Novartis Pharma, Novo Nordisk Pharma, Roche Pharma, Sanofi-Aventis, Swedish Orphan Biovitrum (SOBI), and SYNLAB Holding Deutschland; support for attending meetings or travel, or both, from Amgen; participation on a data safety monitoring board or advisory board with Amgen, Daiichi Sankyo Deutschland, Novartis Pharma Sanofi-Aventis; all outside the submitted work. E Lytvyak reports grants or contracts and consulting fees from Novo Nordisk; payment or honoraria for lectures, presentations, speakers' bureaus, manuscript writing, or educational events from CPD Network and Novo Nordisk; all outside the submitted work. W März reports consulting fees from Amgen, Sanofi, Amryt Pharmaceuticals, Abbott Diagnostics, Akzea Therapeutics, Novartis Pharma, and SOBI; payment or honoraria for lectures, presentations, speakers' bureaus, manuscript writing, or educational events from Amgen, Sanofi, Amryt Pharmaceuticals, Abbott Diagnostics, Akzea Therapeutics, Novartis Pharma, and SOBI; leadership or fiduciary roles in board, society, committee or advocacy groups, paid or unpaid with DACH Society Prevention of Cardiovascular Disease as a Board Member; and other financial or non-financial support from SYNLAB Holding Deutschland; all outside the submitted work. P C Matthews reports support for the present manuscript from Francis Crick Institute (ref CC2223), and University College London NIHR Biomedical Research Centre; outside the submitted work: royalties or licenses from Oxford University Press; honoraria for delivery of educational materials from Johnson & Johnson; and leadership or fiduciary roles in board, society, committee or advocacy groups, paid or unpaid with UK National Strategic Group for Viral Hepatitis (NSGVH) as Co-chair. B Oancea reports support for the present manuscript from the Romanian National Research, Development, and Innovation Plan 2022–27, project PNRR/2022/C9/MCID/I8 number 1672173292, contract number 760231. B M Schaarschmidt reports grants or contracts from Else Kröner-Fresenius Foundation, Deutsche Forschungsgemeinschaft, and PharmaCept; payment or honoraria for lectures, presentations, speakers' bureaus, manuscript writing, or educational events from AstraZeneca, Boston Scientific, and MedMile; support for travel from Bayer; all outside the submitted work. J I Shin reports other financial or non-financial support from the Yonsei Fellowship, funded by Lee Youn Jae, outside the submitted work. D Trico reports payment or honoraria for lectures, presentations, speakers' bureaus, manuscript writing, or educational events from AstraZeneca, Eli Lilly, and Novo Nordisk; support for attending meetings or travel, or both, from AstraZeneca; participation on a data safety monitoring board or advisory board with Amarin, Boehringer Ingelheim, and Novo Nordisk; leadership or fiduciary roles in board, society, committee or advocacy groups, paid or unpaid with European Association for the Study of Diabetes (EASD) Early Career Academy and EASD Committee on Clinical Affairs; receipt of equipment, materials, drugs, medical writing, gifts or other services from Abbott and PharmaNutra; all outside the submitted work. M Zielińska reports other financial or non-financial support as an Alexion, AstraZeneca Rare Disease employee, outside the submitted work. All other authors declare no competing interests. The corresponding author takes responsibility for the accuracy and completeness of these declarations.