行业观察

Science:揭示共价修饰、水分子与阳离子配位介导糖质高级组装的新模式

糖质(glycan)是生命四大基本生物大分子之一,在细胞识别、信号转导、免疫调控和结构支持等多种生理过程中发挥关键作用。历史上,糖质曾常被统称为“碳水化合物”(carbohydrates),这一名称源于其经典化学表达形式Cx(H2O)n;尽管糖质研究可追溯至19世纪,但与蛋白质和核酸相比,糖质科学的发展长期相对滞后。其根本原因在于:糖质太过复杂,一直缺乏有效的研究手段。糖质的生物合成并不像DNA、

发布时间:2026-05-06来源:深圳医学科学院
Nature:身体能够使用泛素蛋白来直接调节储存的糖

我们吃进身体里的糖去哪了?对于这一问题,教科书上会告诉我们,一部分糖用于能量生成,而多余的糖则转化为糖原,储存在肝脏和肌肉中。当身体需要能量供给时,糖原又会被分解为葡萄糖。糖原代谢过程受到一系列酶的精密调控。而过量糖原与许多常见的疾病相关,例如糖尿病、肥胖、肝脏疾病和心脏病。此外,糖原储存疾病是一类罕见的遗传性疾病,患者体内糖原的合成或分解出现异常,这一疾病目前几乎没有治疗选项。最近,《自然》杂志

发布时间:2026-05-06来源:学术经纬
Muscle fat levels on MRI linked to cardiometabolic risk

Radiological Society of North AmericaMay 5 2026 Using a deep learning model to analyze the composition of large muscles on MRI, German researchers found that the proportions of intermuscular fat and l

发布时间:2026-05-04来源:news-medical
New coating prevents protein adhesion to reduce hospital infections

University of Toronto Faculty of Applied Science & EngineeringMay 5 2026 A non-toxic coating developed by researchers at University of Toronto Engineering prevents proteins from sticking to surfaces -

发布时间:2026-05-04来源:news-medical
Single psilocybin dose linked to lasting brain and mood changes

University of California - San FranciscoMay 5 2026 Researchers at UC San Francisco and Imperial College London have shown that a single dose of psilocybin, the psychedelic compound found in magic mush

发布时间:2026-05-04来源:news-medical
Silicosis remains widespread among mineral miners worldwide

National Jewish HealthMay 5 2026 Researchers from National Jewish Health conducted what is believed to be the largest systematic review of silicosis in mineral miners. Silicosis is an irreversible lun

发布时间:2026-05-04来源:news-medical
New method matures lab-grown heart cells for better research

University of Toronto Faculty of Applied Science & EngineeringMay 5 2026 Researchers at the University of Toronto's Institute of Biomedical Engineering have developed a new method to mature lab-grown

发布时间:2026-05-04来源:news-medical
Big tech drives the rise of direct-to-consumer health AI assistants

JMIR PublicationsMay 5 2026 JMIR Publications today released a timely new feature in its News and Perspectives section, providing one of the first comprehensive overviews of the rapidly expanding cons

发布时间:2026-05-04来源:news-medical
Obesity and Alzheimer’s linked through early metabolic disruptions

Florida Atlantic UniversityMay 5 2026 By 2030, the population in the United States aged 65 and older is expected to reach 71 million or about 20% of Americans. This growth is likely to increase the bu

发布时间:2026-05-04来源:news-medical
Non-destructive technique enables repeated transcriptome analysis in living cells

Technical University of Munich (TUM)May 5 2026 Until now, studying the genetic processes in cells required destroying them - making it impossible to observe these processes over extended periods of ti

发布时间:2026-05-04来源:news-medical
YAP1 expression drives chemotherapy resistance in small cell lung cancer

University of Texas M. D. Anderson Cancer CenterMay 5 2026 Researchers from The University of Texas MD Anderson Cancer Center have discovered that some cancer cells express the YAP1 protein only after

发布时间:2026-05-04来源:news-medical
Quagga mussel protein offers new insights into bioadhesives

University of Toronto Faculty of Applied Science & EngineeringMay 5 2026 Researchers at the University of Toronto have identified a protein from the quagga mussel that can stick to surfaces underwater

发布时间:2026-05-04来源:news-medical
Groundbreaking study explores prenatal drug therapy for osteogenesis imperfecta

Shriners Hospitals for ChildrenMay 5 2026 Shriners Children's St. Louis is proud to announce that one of its lead researchers, Dr. Arin Oestreich, has been awarded a $3.1 million R01 grant from the Eu

发布时间:2026-05-04来源:news-medical
Exercise remains essential alongside GLP-1 obesity treatments

Pennington Biomedical Research CenterMay 5 2026 As GLP-1 receptor agonists reshape obesity treatment, a new medical perspective published in the Journal of the American Medical Association, or JAMA, u

发布时间:2026-05-04来源:news-medical
Cruise ship-linked hantavirus cases highlight zoonotic infection risks

Global Virus NetworkMay 5 2026 The Global Virus Network (GVN), representing eminent human and animal virologists from more than 90 Centers of Excellence and Affiliates in over 40 countries dedicated t

发布时间:2026-05-04来源:news-medical