行业观察

Physiological febrile heat stress increases cytoadhesion through increased protein trafficking ofsurface proteins into the red blood cell

AbstractFever is a hallmark of malaria. Several studies have linked febrile temperatures to reduced parasite viability, but also to increased cytoadhesion, a key driver of pathology. However, differen

发布时间:2026-03-31来源:e life
A novel RAB5 binding site in human VPS34-CII that is likely the primordial site in eukaryotic evolution

AbstractRAB5-GTP activation of the multiprotein VPS34 complex II (VPS34-CII) is critical for endosomal sorting and maturation, phagocytosis, and receptor downregulation. RAB5-GTP activates VPS34-CII,

发布时间:2026-03-31来源:e life
The CLAMP GA-binding transcription factor regulates heat stress-induced transcriptional repression

AbstractTo survive exposure to heat stress (HS), organisms activate stress response genes and repress constitutive gene expression, thereby preventing the accumulation of potentially toxic RNA and pro

发布时间:2026-03-31来源:e life
Direction and orientation preferences in mouse superior colliculus and its retinal inputs exhibit a topography of cardinal biases atop locally mixed tuning

AbstractIn mouse superior colliculus (SC), neurons are robustly tuned to motion direction and orientation, but it remains controversial whether these preferences form global maps or are arranged in a

发布时间:2026-03-31来源:e life
Adaptive evolution to thermal stress underpins climate resilience in a cosmopolitan arthropod

AbstractAdaptive evolution enables species to survive and thrive under changing environmental conditions. In the face of accelerating global climate change, thermal stress represents a major challenge

发布时间:2026-03-31来源:e life
Slap restricts oncogenic Src-family kinase signaling to maintain colonic epithelial homeostasis

AbstractSrc-family kinases (SFKs) regulate proliferation in colonic epithelial cells (CECs), but the mechanisms that restrain their activity remain poorly defined. We identify Src-like adaptor protein

发布时间:2026-03-31来源:e life
Point of View: An easy way to improve lab meetings

Abstract Sharing positive and negative experiences at lab meetings can make a career in science a little less hard, a little more pleasant, and a little more human. Main text Most scientists are part

发布时间:2026-03-17来源:e life
Neuropathic Pain: Closing in on the causes of chronic neuropathic pain

Geoffroy Laumet Department of Physiology, Michigan State University, United States; Neuropathic pain develops when nerve damage causes the pain-sensing pathways in the nervous system to become hyperse

发布时间:2026-03-17来源:e life
Membrane Proteins: A missing link for efflux pumps

Hilal WehbiIsabelle Broutin Laboratoire CiTCoM, Faculté de Santé, Université Paris Cité and CNRS, France; We have become used to treating bacterial infections with antibiotics, but in recent decades t

发布时间:2026-03-24来源:e life
Gut Microbiome: Bacteria weigh up costs and benefits of mobile weapons

Zhao WangYang Fu Department of Biochemistry, SUSTech Homeostatic Medicine Institute, School of Medicine, Southern University of Science and Technology, China; Mammals have communities of microbes in t

发布时间:2026-03-22来源:e life
Psychedelic Drugs: Reshaping human neurons

Jessica L MaltmanJavier González-Maeso Biomedical Sciences Graduate Program, Virginia Commonwealth University School of Medicine, United States; Department of Pharmacology and Toxicology, Virginia Com

发布时间:2026-03-30来源:e life
[推荐] VMRack洛杉矶CN2GIA精品线路高速VPS服务器 低至49美元/年

VMRack主要在美国洛杉矶运营自建机房并提供虚拟机和独立服务器 , 这些服务器均采用精品线路确保全球高速畅联。 线路方面主要采用CN2GIA、AS9929/AS10099、CMIN2等 ,国内平均延迟140~200毫秒,线路连接方面非常稳定。 因此无论是中国电信、中国联通还是中国移动用户都能通过VMRack服务器快速连接 , 可以用来建站或运行容器应用。 精品线路说明: VMRack美国洛杉矶L

发布时间:2026-03-27来源:蓝点网
新浪云(SAE)将在9月16日彻底凉凉 你还记得曾经的SAE贴吧签到脚本吗?

#云计算 新浪云 (SAE) 将在 9 月 16 日彻底凉凉,你还记得曾经的 SAE 贴吧签到脚本吗?在蓝点网印象里新浪云早就半死不活了,好像也就早期推出 SAE 时火过一段时间,彼时免费额度拿来跑贴吧签到等小脚本非常爽。查看全文:https://ourl.co/112221据新浪云团队发布的公告,新浪云将在 2026 年 9 月 16 日 24 时起下线并永久终止服务,终止服务后所有用户的数据将

发布时间:2026-03-18来源:蓝点网
百度智能云宣布对AI算力和存储等产品涨价 涨幅约5%起 最高涨幅30%

#云计算 百度智能云宣布对 AI 算力产品及相关服务以及 PFS 并行文件存储等产品涨价,涨幅约 5%~30%。百度智能云给出的理由是 AI 算力需求持续攀升,核心硬件及相关基础设施成本出现显著上涨。新价格将在 4 月 18 日生效。查看全文:https://ourl.co/112246百度智能云平台日前发布产品调价公告,宣布对 AI 算力相关产品或服务以及并行文件存储等服务调整价格,其中 AI

发布时间:2026-03-19来源:蓝点网
阿里云宣布对AI算力和存储产品涨价 包括ECS服务器和RDS数据库等也涨价

#云计算 阿里云宣布对 AI 算力和存储产品涨价,包括 ECS 服务器和 RDS 数据库等也涨价,部分规格涨幅达 25%~34%。阿里云给出的涨价原因是全球 AI 需求爆发式增长导致整个供应链都在涨价,行业核心硬件采购成本显著增长,新价格将在 4 月 18 日生效。查看全文:https://ourl.co/112245阿里云于 2026 年 3 月 18 日发布公告,宣布对旗下多款产品价格进行调整

发布时间:2026-03-19来源:蓝点网