行业观察

WileyApr 8 2026 A study in Health Economics provides strong evidence that public long‐term care insurance can vastly reduce the crushing financial burden of end‐of‐life health care. When investigators

导读：治疗甲状腺眼病 4月6日，安进公司宣布，其2025年销售额达19.03亿美元（约合人民币131亿元）的重磅药物TEPEZZA，在采用皮下注射给药方式的3期临床试验中取得积极顶线结果，展现出与静脉输注剂型相当的有效性。这项随机、双盲、安慰剂对照的3期临床试验结果显示，在24周的治疗期内，TEPEZZA OBI组的患者眼球突出缓解率高达77%（76.7%vs安慰剂组19.6%，p<0.0001）

AbstractVestibular hair cells (HCs) convert gravitational and head motion cues into neural signals through mechanotransduction, mediated by the hair bundle—a mechanically integrated organelle composed

当前，中国医疗健康行业正站在结构性变革的关键路口。一方面，105.5万个基层医疗卫生机构支撑起了全国范围内远超50%的诊疗量。但是，基层医疗仍旧深陷人才不足、能力薄弱、信任缺失、服务低效的长期困境；另一方面，医药企业面临集采控费、合规趋严、进院受阻等问题，在数字化转型的当下，亟须寻找新的增长点。而基层医疗普遍被视为医药企业实现增长的突破口。如今，“十五五”规划进一步将基层医疗卫生服务作为重要规划内

Metaphore possesses a next-generation platform that enhances drug discovery utilising AI technology Metaphore拥有一个利用人工智能技术增强药物发现的下一代平台。image credit- shutterstock 图片来源：shutterstockJapan-based TOHO HOLDI

ZEISS Vision Care acquired key assets of Vivior AG, a Swiss-based innovator in digital health technologies for eye care, thereby strengthening its research capabilities and innovation potential in thi

Abstract Polyphosphate (polyP) exists in all life forms; however, its biological functions in metazoans are understudied. Here, we explored Drosophila, to our knowledge, as the first genetic model to

AbstractAlpha-band neural oscillations (8–13 Hz) are theorized to phasically inhibit visual processing based, in part, on results showing that pre-stimulus alpha phase predicts detection (i.e., hit ra

Abstract Although division of labor as a means to increase productivity is a common feature in animal social groups, most previous studies have focused almost exclusively on eusocial insects with extr

Abstract GID/CTLH-type E3 ligases assemble into conserved ring-shaped architectures built from repeating LisH-CTLH-CRA modules, yet the molecular rules that enforce their highly specific subunit arran

Abstract The positioning of limbs along the anterior-posterior axis varies widely across vertebrates. The mechanisms controlling this feature remain to be fully understood. For over 30 years, it has b

Abstract The identification of cell types remains a major challenge. Even after a decade of single-cell RNA sequencing (scRNA-seq), reasonable cell type annotations almost always include manual non-au

Ana S RamírezCamilo Perez Department of Biochemistry and Molecular Biology, University of Georgia, United States; Complex Carbohydrate Research Center, University of Georgia, United States; From proka

By Dr. Priyom Bose, Ph.D.Reviewed by Lauren HardakerApr 8 2026 New evidence suggests common viral infections may shape dementia risk, while vaccination and antiviral therapies could offer a surprising

对于激素受体阳性的乳腺癌患者来说，芳香化酶抑制剂是控制肿瘤的重要武器。它通过抑制雌激素生成来阻断肿瘤生长信号，但雌激素的缺失也让骨骼和肌肉付出代价：骨量流失加速、肌肉无力、脂肪堆积。这些问题不仅影响生活质量，还可能导致患者中断治疗，反而影响预后。有没有一种既能保护骨骼肌肉、又不增加身体负担的方法？ 近日，Nat Commun上发表的研究给出了新思路。他们发现，一种名为低强度振动的物理干预，每天仅需