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AbstractBenzoylphenylurea (BPU) insecticides disrupt insect chitin formation, yet their molecular target is debated. Although resistance-associated mutations map to the Chitin Synthase (CHS) gene, dir

AbstractTopographic organization, whereby neighboring cortical locations encode neighboring features in sensory or cognitive space, is a fundamental principle of brain function. Existing approaches fo

AbstractTracking prey or recognizing a lurking predator is as crucial for survival as anticipating their actions. To guide behavior, the brain must extract information about object identities and thei

AbstractAfrican trypanosomiasis is a neglected tropical disease transmitted by tsetse flies (Glossina spp.) in sub-Saharan Africa. The fly’s saliva carries parasitic unicellular trypanosomes, such as

各有关单位： 当前，“医学+AI”已从技术探索迈入规模化应用新阶段，深刻重塑临床医学科研范式，为破解科研效率偏低、数据挖掘不足等痛点提供了全新路径。在健康中国战略指引下，临床医学科研正从经验驱动向数据驱动转型，亟需兼具临床专业素养与人工智能应用能力的复合型人才。为精准对接国家医工交叉战略趋势，助力医学领域科研人员深度掌握人工智能技术，提升实操应用能力，推动科研事业高质量发展，我中心将于2026年5

依苏巴格鲁肽（Efsubaglutide）α是一种长效人源化 GLP-1 受体激动剂，本研究评估其在二甲双胍基础上追加联合治疗成人2 型糖尿病的临床效果。 2026年5月8日，复旦大学王庆华、上海交通大学贾伟平共同通讯在Nature Communications（IF=15.7）在线发表题为Efsubaglutide alfa added to metformin improves glycaem

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Abstract A large fraction of newly transcribed RNA is degraded in the nucleus, but nuclear mRNA degradation pathways remain largely understudied. The yeast nuclear endoribonuclease Rnt1 has a well-cha

Abstract An endogenous circadian clock controls many of the behavioral traits of Drosophila melanogaster. This ‘clock’ relies on the activity of interconnected clusters of neurons that harbor the cloc

Abstract The greatest mass extinction at the end of the Permian, ca. 252 million years ago, led to a tropical dead zone on land and sea. The speed of recovery of life has been debated, whether fast or

NASA’s Psyche spacecraft will fly close to Mars on Friday in a crucial manoeuvre that could bring scientists closer to understanding the birth of Earth. ADVERTISEMENT ADVERTISEMENT The flyby will use

2026年5月，礼来在欧洲肥胖大会（ECO）年会上披露了Bimagrumab减重BELIEVE最新临床数据。BELIEVE共分为8个队列，入组507例受试者，治疗72周，停药32周继续观察，设置6个时间点DXA扫描身体成分。Bimagrumab的增肌效果已经非常明确，但停药24周增加的肌肉全部损失，回落至基线以下，反而是司美格鲁肽单药治疗组损失的肌肉一并反弹，停药24周后肌肉质量相差已经不大。总结

想象一下，如果我们的眼睛不仅能“看”光，还能像植物一样“用”光来生产能量、修复自身，那会怎样？2026年5月15日，新加坡国立大学梁大卫、浙江大学叶娟、山东第一医科大学/山东省医学科学院孙晓及南京邮电大学丁晓光共同通讯在Cell 在线发表题为“Transplanting light-dependent reactions for mammalian eye photosynthesis”的研究论文

在中年及以后保持身材匀称并非易事。从中年时期开始，成年人往往会遭受内脏脂肪堆积以及相关不良的代谢紊乱。在老鼠和人类（尤其是男性）身上，内脏脂肪往往会增多。近期，美国希望之城医学中心王琼团队联合加州大学洛杉矶分校杨霞团队（王冠和李高岩为该论文共同第一作者）在Science 在线发表题为“Distinct adipose progenitor cells emerging with age drive

5月15日，第一三共与阿斯利康共同宣布，Enhertu（德曲妥珠单抗）在美国新增两项适应症。1）联合THP方案（紫杉醇+曲妥珠单抗+帕妥珠单抗）新辅助治疗手术前的高风险HER2阳性（IHC 3+或ISH+）早期（2期或3期）乳腺癌成人患者；2）术后辅助治疗在接受曲妥珠单抗+紫杉醇±帕妥珠单抗方案作为新辅助治疗后出现残留性浸润性疾病的HER2阳性（IHC 3+或ISH+）乳腺癌成人患者。新辅助治疗和